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Preclinical studies in rodents have demonstrated reductions in fat mass, improved insulin sensitivity, and increased metabolic rate without significant changes to food intake (Neelakantan et al., 2019)

PMID: 12459848

People with Medical Conditions Peptide therapy should always be supervised by a healthcare professional, especially for individuals with pre-existing medical conditions

This mechanism is not fully elucidated and it is possible that it acts via the IGF-1 receptor (not GHR) in localized concentrations

When administered, Sermorelin mimics GHRH, stimulating pulsatile growth hormone secretion , which is crucial for downstream production of insulin-like growth factor 1 (IGF-1) in the liver

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